Mitogenic activities in African traditional herbal medicines were examined on human
peripheral blood lymphocytes and mouse spleen cells using protein fractions obtained from
their extracts by precipitation with ammonium sulfate. Target specificity for these mitogens
was investigated by using isolated T cells and lymphocytes from athymic nude mice. Among
20 plants investigated, potent mitogenic activities for both human and mouse lymphocytes
were found in 7 plants: Monanthotaxis sp.(Annonaceae), Uvaria lucida (Annonaceae) …